CURRICULUM  VITAE

YITZHAK PILPEL

Incumbent of the Aser Rothstein career development chair in genetic diseases

Born:   September 12, 1968, Jerusalem, Israel.

Current Position: Senior Scientist at the Department of Molecular Genetics, the Weizmann Institute of Science

Address: Weizmann Institute of Science, Rehovot, 76100, Israel

Fax: 972-8-934-4108

Phone: 972-8-934-6058

Email: pilpel@weizmann.ac.il

WWW: http://longitude.weizmann.ac.il

 

 

EDUCATION

1990-1993       B.Sc. in Biology at the Tel Aviv University. Graduated Cum Laude.

1993-1994       Studies towards M.Sc. at the Feinberg Graduate School of the Weizmann Institute of Science. Transferred to the direct path to Ph.D.

1995-1999       Ph.D. studies with distinction at the Weizmann Institute of Science, under the supervision of Prof. Doron Lancet and Prof. Ephraim Katchalski-Katzir. Thesis title: "Structural and evolutionary genomics of molecular recognition repertoires"

 

AWARDS AND HONORS

1998    First prize in the national competition for multidisciplinary Ph.D. study awarded by the Dean of the faculty of Mathematics and Natural Sciences, The Hebrew University, Jerusalem.

2000    Prize of Distinction for outstanding Ph.D. studies at the Feinberg Graduate School, Weizmann Institute of Science.

2005    EMBO Young Investigator award.

2006    James Heineman Award

 

SCHOLARSHIPS

1997    A Fellowship of Distinction for "outstanding achievement in studies and research" awarded the Dean of the Feinberg Graduate School, the Weizmann Institute of Science.

1997-1998       John F. Kennedy Memorial Fund Scholarship from the Feinberg Graduate School, the Weizmann Institute of Science.

2000    Fulbright post-doctoral award.

2002    Fellow of the PhRMA Foundation –a Center for Excellence in Integration of Genomics and Informatics at Harvard University

2003-2006 Fellow of the Horowitz Foundation for Complexity Sciences – a merit-based fellowship for young Principal Investigators.

 

POSITIONS

1990-1992       Research Assistant, Department of Botany, Tel Aviv University, with Prof. Roni Aloni. Subject: Anatomy and physiology of root development.

1992-1993       Research Assistant, Department of Molecular Microbiology and Biotechnology, Tel Aviv University, with Dr. Daniel Segal. Subject: genetic analysis of Drosophila embryonic development.

1996-1999       Research Associate in the Center for the Study of Molecular Recognition headed by Prof. Ephraim Katchalsky-Katzir at the Weizmann Institute of Science. Subject: algorithms for protein docking.

1999-2002       Post-doctoral research fellow with Dr. George M. Church, Department of Genetics,  and Lipper Center for Computational Genetics, Harvard Medical School

2000-2001       Consultant for Pfizer Inc., Cambridge, MA. Subject: Sequence, structure and function in G protein-coupled receptors.

2003- Senior Scientist, department of Molecular Genetics, Weizmann Institute of Science.

 

EDITORIAL APPOINTMENTS

PLoS Computational Biology (associate editor on selected papers)

Biology Direct

CONFERENCE PROGRAM COMMITTEE

RECOMB Regulatory genomics 2004

RECOMB Regulatory genomics and systems biology 2005

RECOMB 2005

RECOMB Regulatory genomics 2006

 

TEACHING

1992-1993       Teaching Assistant in mathematics, in the course “Introduction to Differential and Integral Calculus”, Tel Aviv University.

1996    Teaching Assistant in the course "Receptors and Recognition" at the Feinberg Graduate School, the Weizmann Institute of Science.

1998    Lecturer in the course "Computational Genomic and Bioinformatics" at the Feinberg Graduate School, the Weizmann Institute of Science.

1999    Teaching Assistant in the course "Programming for Bioinformatics and Internet" at the Feinberg Graduate School, the Weizmann Institute of Science.

2003-present  Lecturer in the course: "Computational Functional Genomics”, at the Feinberg Graduate School, the Weizmann Institute of Science.

 

RECENT INVITED LECTURES

15. Differential gene expression regulation and species divergence. International course on "Global interrogations of biological processes", ISREC, Lausanne, November 2006.

14. Differential gene expression regulation and species divergence. Systems Biology and Evolution work shop, Imperial College London, October 2006.

13. Comparative genomics of translation regulation Chicago University, August 2006.

12. Responsive backup circuits. Boston University, July 2006

11. Comparative genomics of translation regulation Harvard University, July 2006.

10. Systems biology view of expression regulation The 6th EMBO Young Investigator Meeting, Vienna, May 2006 

9. Coping with genetic and non-genetic perturbations. Lecture series at the Rockefeller Center for Studies in Physics and Biology April 2006.

8. Responsive backup circuits. The yeast systems biology network, Gotenburg, June 2005.

7. Coupled sense and anti-sense regulation. The 3rd Bertinoro Computational Biology Meeting, Bertinoro, June 2005.

6. Transcription control of genetic backup circuits. EMBO Practical Course on Functional Genomics, Milan February 2005

5. Revealing the architecture of genetic backup circuits through inspection of transcription regulatory networks. The first annual RECOMB meeting on Regulatory Genomics. University of California San-Diego, San-Diego March 2004.

4. Computational dissections of genetics regulatory networks. The 6th Israeli bioinformatics conference, Haifa, 2003.

3. Computational detection and analysis of regulatory SNPs. The Nordic Bioinformatics conference, Helsinki, 2003.

2. Promoter sequence and the thermodynamics of DNA-protein interactions. 2nd Annual McGill Workshop on Computational Biology, Barbados, 2003.

1. Computational identification of genetics regulatory networks. DIMACS Workshop on Integration of Diverse Biological Data, Rutgers University, NJ. 2001.

 

REFEREED CONFERENCE LECTURES (in computer science-oriented meetings)

  1. Genome-wide transcription regulatory circuits controlling cellular malignant transformation ISMB 2005 (one of 50 talks selected for oral presentation from 500 submissions; Best poster award)
  2. Transcriptional reprogramming in genetic backup circuits ISMB 2005 (one of 50 talks selected for oral presentation from 500 submissions)

3.      Characterization of the effects of TF binding site variations on gene expression: Towards predicting the functional outcomes of regulatory SNPs RECOMB Regulatory genomics and systems biology 2005

  1. Backup by paralogs decouples genes lethality from centrality: evidence for preferential backup of hubs RECOMB Regulatory genomics and systems biology 2005
  2. Phenotypic divergence correlates with translational control signals in protein coding sequences in yeast species RECOMB Regulatory genomics and systems biology 2005